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Table 3 Novel GWS loci from combined ASD-schizophrenia GWAS

From: Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

SNP Locus range A1 Odds ratio (95% CI) P value Genes within locus
ASD SCZ Combined
rs57709857 chr8:38014429..38316849 A 0.92 (0.86–0.97) 0.93 (0.91–0.96) 0.93 (0.91–0.95) 4.2 × 10−9 BAG4 DDHD2 FGFR1 LETM2 LSM1 PLPP5 WHSC1L1
rs1353545 chr3:60276185..60305117 C 1.05 (1.00–1.10) 1.06 (1.04–1.09) 1.06 (1.04–1.08) 1.1 × 10−8 FHIT
rs6803008 chr3:71433554..71679148 T 0.94 (0.90–0.99) 0.95 (0.93–0.97) 0.94 (0.93–0.96) 1.3 × 10−8 FOXP1 MIR1284
rs2828478 chr21:25092482..25219939 A 1.07 (1.02–1.12) 1.06 (1.04–1.08) 1.06 (1.04–1.08) 1.6 × 10−8 None
rs9879311 chr3:10317432..10520739 T 1.08 (1.03–1.13) 1.05 (1.03–1.08) 1.06 (1.04–1.08) 1.9 × 10−8 ATP2B2 GHRL GHRLOS LINC00852 MIR378B MIR885 SEC13 TATDN2
rs73416724 chr6:43234901..43411659 A 1.11 (1.03–1.20) 1.09 (1.05–1.13) 1.09 (1.06–1.13) 3.0 × 10−8 ABCC10 CRIP3 MIR6780B SLC22A7 TTBK1 ZNF318
rs61847307 chr10:53935082..54035437 T 0.95 (0.90–1.00) 0.94 (0.92–0.96) 0.94 (0.92–0.96) 3.1 × 10−8 PRKG1
rs7122181 chr11:81178475..81209569 A 0.95 (0.91–1.00) 0.95 (0.93–0.97) 0.95 (0.93–0.97) 3.7 × 10−8 None
rs880446 chr20:62113220..62178105 A 1.07 (1.02–1.13) 1.06 (1.04–1.09) 1.06 (1.04–1.09) 4.4 × 10−8 EEF1A2 PPDPF PTK6 SRMS
rs7521492 chr1:163581663..163790947 A 1.05 (1.00–1.10) 1.06 (1.03–1.08) 1.06 (1.04–1.08) 4.7 × 10−8 None
rs72986630 chr19:11849736..11943697 T 1.07 (0.95–1.21) 1.16 (1.10–1.22) 1.14 (1.09–1.20) 4.7 × 10−8 ZNF440 ZNF441 ZNF491 ZNF823
rs4904167 chr14:84628384..84701798 T 1.08 (1.03–1.14) 1.05 (1.03–1.07) 1.06 (1.04–1.08) 4.9 × 10−8 None