Mecp2 DEGs
|
M1/M2 expression
|
Shared genes
|
p value
|
---|
5 week (n = 464)
|
M1 down
|
28
|
1.83E−04
|
M1 up
|
28
|
1.34E−05
|
M2 down
|
13
|
3.21E−02
|
M2 up
|
34
|
1.86E−12
|
24 week (n = 79)
|
M1 down
|
8
|
2.10E−03
|
M1 up
|
6
|
1.44E−02
|
M2 down
|
7
|
2.68E−04
|
M2 up
|
8
|
7.90E−05
|
- DEGs in 5- and 24-week microglia identified in this study were compared with genes activated to produce M1 and M2 macrophages from a baseline state (M0) in mouse [55]. The p values for the gene overlaps were determined by Fisher’s exact test