Skip to main content

Table 1 Differentially expressed heat shock genes in 5-week RTT microglia

From: Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

  5 weeks 24 weeks
Gene FC p value padj FC p value padj
Dnaja1 −0.88 7.20E−14 3.78E−10 −0.02 8.58E−01 9.92E−01
Hspa8 −0.58 1.48E−11 2.59E−08 0.08 5.66E−01 9.45E−01
Dnajb1 −0.70 2.01E−11 2.88E−08 0.02 8.88E−01 9.93E−01
Hspb8 −0.96 5.09E−09 2.67E−06 0.08 5.66E−01 9.45E−01
Hsph1 −0.90 1.64E−06 2.90E−04 0.00 NA NA
Hspa1b −0.73 1.80E−05 2.08E−03 −0.02 7.89E−01 9.86E−01
Hspa2 −0.54 3.92E−05 3.89E−03 0.15 2.67E−01 8.50E−01
Hspa12b −0.67 4.09E−05 3.98E−03 −0.14 3.37E−01 8.78E−01
Hsp90aa1 −0.43 4.30E−04 2.27E−02 −0.12 3.00E−01 8.59E−01
  1. FC is log2(fold change of RTT/WT); p value indicates nominally significant differences, padj is the p value adjusted for multiple testing using the Benjamini-Hochberg method [37].