Fig. 5
From: Neurogenetic analysis of childhood disintegrative disorder
CDD whole-brain fMRI analysis. a The red color brain map indicates regions of significant faces > houses activation in the CDD subjects (Z > 3.09, whole-brain corrected at the cluster-level P < 0.05). b The bar graph indicates the mean % signal change (faces > houses) within these areas for each cohort: TD:discovery (n = 12), TD:validation (n = 7), HFASD (n = 14), LFASD (n = 7), and CDD (n = 7). The CDD cohort differed significantly from HFASD [t(19) = 2.98, P = 0.0076, Cohen’s d = 1.45] but not from LFASD [t(12) = 1.71, P = 0.11, Cohen’s d = 0.99]. Error bars indicate standard error of the mean. All P values were calculated by independent t test and are two-tailed. MFG middle frontal gyrus, PG precentral gyrus