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Table 5 GSEA of RAVs in the High-5HT group before and after correcting for gene length (italics: p < 0.05)

From: Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

  Before correction After correction
RBFOX1-1 (186) 1 (0.413) 0.5
RBFOX1-2 (547) 3 (0.204) 0.57
FMRP-1 (936) 5 (0.126) 0.68
FMRP-2 (831) 10 (9.108e−05) 0.051
ECGs (928) 3 (0.497) 0.95
Hpsd (1429) 5 (0.385) 0.46
PSD-95 (107) 0 (1.000) 1
ARC (25) 0 (1.000) 1
mGluR5 (37) 1 (0.100) 0.18
NMDAR (59) 0 (1.000) 1
Presynaptic active zone (204) 0 (1.000) 1
Presynaptic (330) 2 (0.242) 0.24
Vesicles (104) 0 (1.000) 1
CRFs (55) 1 (0.145) 0.26
HMEs (146) 0 (1.000) 1
DEs (411) 1 (0.695) 0.57
TADA-1 (33) 2 (3.958e03) 0.03
TADA-2 (63) 1 (0.165) 0.34