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Table 5 GSEA of RAVs in the High-5HT group before and after correcting for gene length (italics: p < 0.05)

From: Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

 

Before correction

After correction

RBFOX1-1 (186)

1 (0.413)

0.5

RBFOX1-2 (547)

3 (0.204)

0.57

FMRP-1 (936)

5 (0.126)

0.68

FMRP-2 (831)

10 (9.108e−05)

0.051

ECGs (928)

3 (0.497)

0.95

Hpsd (1429)

5 (0.385)

0.46

PSD-95 (107)

0 (1.000)

1

ARC (25)

0 (1.000)

1

mGluR5 (37)

1 (0.100)

0.18

NMDAR (59)

0 (1.000)

1

Presynaptic active zone (204)

0 (1.000)

1

Presynaptic (330)

2 (0.242)

0.24

Vesicles (104)

0 (1.000)

1

CRFs (55)

1 (0.145)

0.26

HMEs (146)

0 (1.000)

1

DEs (411)

1 (0.695)

0.57

TADA-1 (33)

2 (3.958e−03)

0.03

TADA-2 (63)

1 (0.165)

0.34