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Table 4 NGSEA to identify novel signals in different groups of DNVs (italics: p < 0.05)

From: Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

  AutDB Recur MAGI1 MAGI2 MAGI3 DAWN1 DAWN2 DAWN3 DAWN4
LoFs 0.838 0.07 0.225 0.326 0.224 0.187 0.52 0.502 0.748
Mis-D2 0.762 0.135 0.026 0.347 0.371 0.083 0.274 0.353 0.055
High-5HT_Func 0.734 0.467 0.178 0.759 0.83 0.027 0.335 0.376 0.244
High-5HT_LoFs 0.925 0.234 0.746 0.713 0.637 0.039 0.653 0.82 0.755
Normal-5HT_LoFs 0.481 0.046 0.139 0.147 0.104 0.33 0.801 0.233 0.506
High-5HT_Mis-D2 0.552 0.512 0.098 0.637 0.748 0.04 0.187 0.235 0.137
Normal-5HT_Mis-D2 0.612 0.1 0.031 0.249 0.25 0.174 0.207 0.329 0.035