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Table 4 Secondary longitudinal analysis results for fractional anisotropy and behavior for HR-ASD

From: Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism

Variable

χ2

q

e B

CI

RBS-R

 Lower order

  ATR FA

1.2

0.33

1.05

0.96–1.14

  CST FA

0.0

0.84

1.01

0.93–1.09

  Genu FA

5.7

0.05

1.09

1.02–1.17

  MCP FA

6.2

0.048

1.07

1.01–1.12

  SCP FA

6.7

0.04

1.13

1.03–1.23

 Higher order

  ATR FA

4.2

0.08

1.10

1.00–1.20

  CST FA

0.6

0.42

1.04

0.95–1.13

  Genu FA

25.3

<0.001

1.21

1.12–1.30

  MCP FA

6.9

0.04

1.08

1.02–1.14

  SCP FA

4.4

0.07

1.11

1.01–1.23

SEQ

 Hypo

  ATR FA

0.7

0.42

1.01

0.98–1.05

  CST FA

0.0

0.86

1.00

0.97–1.03

  Genu FA

14.3

0.002

1.05

1.02–1.07

  MCP FA

11.5

0.007

1.03

1.01–1.05

  SCP FA

5.0

0.07

1.04

1.01–1.07

 Hyper

  ATR FA

0.7

0.42

1.01

0.99–1.04

  CST FA

0.1

0.75

1.00

0.98–1.03

  Genu FA

4.5

0.07

1.02

1.00–1.05

  MCP FA

2.1

0.24

1.01

1.00–1.03

  SCP FA

4.9

0.07

1.03

1.00–1.06

 Seeking

  ATR FA

1.3

0.33

0.98

0.93–1.02

  CST FA

1.1

0.35

0.98

0.94–1.02

  Genu FA

1.6

0.31

1.02

0.99–1.06

  MCP FA

1.3

0.33

1.02

0.99–1.04

  SCP FA

2.6

0.19

1.04

0.99–1.09

  1. Results for generalized estimating equations
  2. RBS-R Repetitive Behavior Scale-Revised, SEQ Sensory Experiences Questionnaire, ATR anterior thalamic radiation, CST cortico-spinal tract, SCP superior cerebellar peduncle, MCP midcerebellar peduncle
  3. q false-discovery rate adjusted p value, e B exponentiated regression coefficient representing percent of increase in score for every hundredth unit increase in fractional anisotropy, CI 95% confidence interval
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Molecular Autism

ISSN: 2040-2392