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Fig. 2 | Molecular Autism

Fig. 2

From: Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation

Fig. 2

Social approach behavior in juvenile offspring who were exposed to prenatal immune challenge (POL) or prenatal vitamin D treatment (VitD). a Compared with control mice poly(I:C)-treated offspring spent less time with a novel conspecific compared to an inanimate object (approaching chance level 50%) demonstrating impaired social approach behavior (*P < 0.05). This impairment was not evident when VitD was co-administered (#P = 0.06) suggesting VitD blocked the negative effects of MIA on social functions. b Prenatal exposures had no effects on locomotion in this test. All values are mean ± SEM (n = 8)

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