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Table 2 Differentially expressed ncRNAs

From: CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

Gene_name Gene_type NPC_binding Log2FC Padj
DLX6-AS1 antisense 0 5.34E + 00 3.85E-86
EMX2OS antisense 0 1.10E + 00 3.79E-02
LINC00340 lincRNA 1 −7.78E-01 1.54E-04
TERC lincRNA 0 −1.07E + 00 1.18E-03
CRNDE lincRNA 1 −9.63E-01 1.39E-02
MEG3 lincRNA 1 −1.24E + 00 1.39E-02
RMST processed_transcript 0 −1.23E + 00 6.41E-07
MIAT processed_transcript 1 −1.28E + 00 6.10E-06
NEFL processed_transcript 0 −1.18E + 00 2.08E-04
TMEM191A processed_transcript 0 −7.74E-01 1.33E-02
SPPL2B processed_transcript 1 −6.41E-01 2.32E-02
SCARNA22 sense_intronic 0 −1.31E + 00 1.56E-03
SNHG3 sense_intronic 1 −7.94E-01 1.41E-02
SOX2-OT sense_overlapping 1 9.29E-01 9.81E-04
SNORA31 snoRNA 0 −1.03E + 00 2.41E-02
SNORA7B snoRNA 1 −1.03E + 00 3.30E-02
SCARNA13 snoRNA 0 −7.08E-01 3.77E-02
SNORA73B snoRNA 1 −7.89E-01 4.61E-02
RNU2-59P snRNA 0 −9.94E-01 1.76E-02
RNU6-15P snRNA 0 −1.07E + 00 4.99E-02
  1. FC is fold change: CHD8 +/−/CHD8 ++. Padj is adjusted p value. CHD8 binding based on ChIP-seq in NPCs by Sugathan et al. [42]