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Table 4 Correlation analyses for the autism spectrum disorder group (a p value of <0.025 served as the criterion of significance)

From: Glutathione metabolism in the prefrontal brain of adults with high-functioning autism spectrum disorder: an MRS study

  AQ EQ WURS-k BDI IQ Age
Anterior cingulate cortex (n = 24)
GSH 0.077 −0.193 0.287 −0.006 −0.549 −0.567
0.721 0.366 0.174 0.978 0.005 0.004
Cre 0.183 −0.373 −0.103 −0.082 −0.329 −0.310
0.393 0.072 0.632 0.702 0.117 0.140
t-Cho 0.286 −0.268 0.063 0.010 −0.106 −0.195
0.175 0.206 0.770 0.964 0.622 0.360
Glx 0.301 −0.394 0.104 −0.019 −0.370 −0.346
0.152 0.057 0.628 0.931 0.075 0.098
NAA 0.363 −0.399 −0.007 −0.102 −0.297 −0.310
0.081 0.053 0.974 0.634 0.159 0.140
mI −0.011 −0.040 −0.013 −0.057 −0.289 −0.339
0.959 0.853 0.952 0.793 0.171 0.105
Dorsolateral prefrontal cortex (n = 24)
GSH −0.014 −0.058 0.126 0.154 −0.020 −0.166
0.950 0.790 0.556 0.471 0.927 0.438
Cre 0.042 −0.176 −0.287 −0.283 −0.136 −0.115
0.847 0.410 0.173 0.180 0.527 0.593
t-Cho −0.226 0.443 −0.010 −0.027 0.434 0.097
0.289 0.030 0.964 0.901 0.034 0.653
Glx −0.079 0.162 0.312 −0.179 −0.454 −0.730
0.713 0.450 0.138 0.402 0.026 0.000
NAA −0.038 −0.297 0.183 0.033 −0.341 −0.391
0.861 0.159 0.391 0.880 0.103 0.059
mI −0.205 0.310 0.004 −0.349 0.005 0.035
0.336 0.141 0.987 0.094 0.982 0.870
  1. Presented are the Pearson correlation coefficients (above) and p values (below)
  2. Significant results are depicted in italics
  3. AQ autism quotient, EQ empathy quotient, WURS Wender Utah Rating scale, BDI Beck Depression Inventory score, IQ intelligence quotient, GSH glutathione, Cre creatine, t-Cho phosphorylcholine + glycerylphosphorylcholine, Glx glutamate + glutamine, NAA N-acetylaspartate, mI myo-inositol (for references, see text)