Fig. 3

Chromatin states and DNA methylation. Box plots of the distribution of methylation in ChromHMM state elements [28], with each point representing one instance of that ChromHMM state in the genome. For each placental ChromHMM state, percent methylation was calculated for each instance of that state in the genome by averaging over the CpG sites in the element and then averaging over all typical (top box) or autism (bottom box) placental samples. In the box plots, the middle dark vertical line is the median, the ends of the box are the interquartile range, and the ends of the whiskers extend to the point within 1.5 times the interquartile range. For easier viewing, outliers were not plotted