Fig. 3
From: A systematic variant annotation approach for ranking genes associated with autism spectrum disorders
Gene scores distribution. a A histogram of the natural logarithm of the total gene score (LnTGS) of the 461 genes associated with autism spectrum disorder in this study. Three genes (ADNP, CHD8, and SHANK3) have distinctly larger scores than all other genes in the dataset. b A scatterplot of the expected LnTGS according to a linear regression model based on the number of variants per gene vs. the observed LnTGS. 95 and 99 % confidence intervals (CI) of the predicted scores are depicted in dotted and dashed lines, respectively