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Table 3 Comparison of questionnaire data for participants with 22qDupNoASD, 22qDupASD, and idiopathic ASD

From: 22q11.2 duplication syndrome: elevated rate of autism spectrum disorder and need for medical screening

  SCQ Total SRS total Vineland-II socialization Vineland-II composite
TDC     
 mean (SD) 1.7a (1.8) 41.9a (5.4) 114.0a (12.7) 113.1a (12.4)
 n 57 73 57 57
DupNoASD     
 mean (SD) 14.1ab (9.7) 68.1ab (17.9) 88.3a (20.2) 86.2a (17.3)
 n 13 14 14 14
DupASD     
 mean (SD) 26.8b (7.8) 91.0b (14.6) 72.8 (10.9) 75.5 (11.2)
 n 5 5 4 4
ASD     
 mean (SD) 21.6 (5.3) 76.6 (15.1) 73.9 (12.4) 77.9 (11.6)
 n 56 68 55 55
  1. Significantly different scores (p < 0.05) between groups on each measure denoted as follows:
  2. aThis value is significantly different between the DupNoASD and Typically Developing Control groups
  3. bThis value is significantly different between the DupNoASD and DupASD groups
  4. Abbreviations: ADHD attention-deficit/hyperactivity disorder, ADI-R Autism Diagnostic Interview-Revised, ADOS Autism Diagnostic Observation Schedule, ASD autism spectrum disorder, CASI-4R Child and Adolescent Symptom Inventory-4R, SCQ Social Communication Questionnaire, SRS Social Responsiveness Scale, TDC typically developing controls, Vineland-II Vineland Adaptive Behavior Scales-II