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Table 1 Group demographics

From: 22q11.2 duplication syndrome: elevated rate of autism spectrum disorder and need for medical screening

  Medical chart review Psychiatric and behavioral Instruments
SRS SCQ Vineland-II CASI-4R ADI-R ADOS
n Age M (SD) % male n Age M (SD) % male n Age M (SD) % male n Age M (SD) % male n Age M (SD) % male n Age M (SD) % male n Age M (SD) % male
ASD 68 7.8 (3.4) 80.9 56 9.0 (2.7) 76.8 55 9.0 (2.7) 76.4 52 9.0 (2.7) 75.0 70 7.8 (3.5) 80.0 70 7.8 (3.5) 80.0
22q11.2DupS 37 14.0 (13.5) 75.7 28 7.1 (3.4) 78.8 21 8.4 (3.0) 81.0 27 7.2 (3.5) 77.8 21 8.4 (3.0) 81.0 20 8.2 (3.2) 80.0 8 8.3 (2.9) 87.5
22q11.2DS 101 8.9 (7.9) 59.4 62 7.6 (3.8) 75.8 53 8.7 (3.5) 77.4 60 7.4 (3.9) 75.0 43 8.8 (3.0) 72.1
TDC 73 7.8 (3.5) 76.7 57 9.3 (2.4) 78.9 57 9.3 (2.4) 78.9 57 9.3 (2.4) 78.9
  1. Children with 22q11.2DS, idiopathic ASD, or TDC were matched on age and sex to the 22q11.2DupS cohort. Each questionnaire was completed on-line. Because the allowable age range differs for each questionnaire, sample sizes vary somewhat across the different study instruments
  2. Abbreviations: ASD autism spectrum disorder, CASI-4R Child and Adolescent Symptom Inventory-4R, SCQ Social Communication Questionnaire, SRS Social Responsiveness Scale, TDC typically developing controls, Vineland-II Vineland Adaptive Behavior Scales-II