| Groups | Test of differences | |||
---|---|---|---|---|---|
 | NAC | Placebo | |||
 | n/total | % | n/total | % | Chi-squarea |
Week 4 | Â | Â | Â | Â | 0.28 |
 Response | 4/15 | 26.7 | 5/14 | 35.7 |  |
 No response | 11/15 | 73.3 | 9/14 | 64.3 |  |
Week 8 | Â | Â | Â | Â | 0.07 |
 Response | 5/13 | 38.5 | 4/12 | 33.3 |  |
 No response | 8/13 | 61.5 | 8/12 | 66.7 |  |
Week 12 | Â | Â | Â | Â | 0.15 |
 Response | 6/12 | 50.0 | 5/11 | 45.5 |  |
 No response | 6/12 | 50.0 | 6/11 | 54.5 |  |