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Table 3 Clinical Global Impression-Improvement scale score, NAC vs. placebo

From: A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder

 

Groups

Test of differences

 

NAC

Placebo

 

n/total

%

n/total

%

Chi-squarea

Week 4

    

0.28

 Response

4/15

26.7

5/14

35.7

 

 No response

11/15

73.3

9/14

64.3

 

Week 8

    

0.07

 Response

5/13

38.5

4/12

33.3

 

 No response

8/13

61.5

8/12

66.7

 

Week 12

    

0.15

 Response

6/12

50.0

5/11

45.5

 

 No response

6/12

50.0

6/11

54.5

 
  1. aOne-tailed significance + p < .10; *p < .05. No p values for these chi-squares reached significance at .05 and ranged from .60 to .79
  2. Response = very much improved (1) or much improved (2); no response = minimally improved (3), no change (4), minimally worse (5); no participants scored much worse (6) or very much worse (7)
  3. NAC N-acetylcysteine