| NAC (n = 16) | Placebo (n = 15) |
---|
Adverse effects | Mild | Mod | Severe | Mild | Mod | Severe |
---|
URI | 9 | 1 | 0 | 5 | 1 | 0 |
Headache | 3 | 0 | 0 | 2 | 1 | 0 |
Stomachache | 2 | 0 | 0 | 2 | 0 | 0 |
Fever | 2 | 1 | 0 | 0 | 0 | 0 |
Irritability | 2 | 0 | 0 | 1 | 0 | 0 |
Insomnia | 2 | 0 | 0 | 0 | 0 | 0 |
Otitis media | 1 | 1 | 0 | 1 | 0 | 0 |
Increased enuresis | 1 | 0 | 0 | 1 | 0 | 0 |
Interrupted sleep | 1 | 0 | 0 | 1 | 0 | 0 |
Localized rash | 1 | 0 | 0 | 1 | 0 | 0 |
Nausea | 1 | 0 | 0 | 1 | 0 | 0 |
Stereotypy | 0 | 0 | 0 | 2 | 0 | 0 |
- The table only lists adverse effects occurring ≥2 times across the samples
- Placebo group reported one moderate case of the following adverse effects: defiant behavior, hives, itchy skin, and threats to hurt self
- Placebo group reported one mild case of the following adverse effects: accidental injury (arm), constipation, diarrhea, dry mouth, emotional outburst, encopresis, increased hyperactivity, self-injurious behavior (skin picking), sinus infection, skin infection, sore throat, urinary tract infection, and weight gain
- NAC group reported one mild case of the following adverse effects: aggression, appetite increase, behavior worse, change in speech, early morning awakening, edema, medical or surgical procedure, swollen neck/lymph nodes, and tic
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NAC N-acetylcysteine, Mod moderate, URI upper respiratory infection