| Groups | Test of differences | |||
---|---|---|---|---|---|
 | NAC | Placebo |  | ||
Characteristics | n/total | % | n/total | % | Chi-squarea |
Gender—male | 12/16 | 75.0 | 12/15 | 80.0 | 0.11 |
Race—White | 16/16 | 100.0 | 14/15 | 93.3 | 1.01 |
Diagnosis | |||||
 Autistic disorder | 7/16 | 43.8 | 7/15 | 46.7 | 0.03 |
 Asperger’s disorder | 2/16 | 12.5 | 5/15 | 33.3 | 1.92 |
 PDD-NOS | 7/15 | 43.8 | 3/15 | 20.0 | 1.98 |
CGI-S | |||||
 Marked (5) | 6/16 | 37.5 | 9/15 | 60.0 | 1.57 |
 Severe (6) | 9/16 | 56.3 | 6/15 | 40.0 | 0.82 |
 Extreme (7) | 1/16 | 6.3 | 0/15 | 0.0 | 0.97 |
Concomitant medication (y/n) | 6/16 | 37.5 | 10/15 | 66.7 | 2.64 |
Medication types | |||||
 Psychostimulants | 3/16 | 18.7 | 3/15 | 20.0 | 0.01 |
 Alpha 2 agonists | 1/16 | 6.2 | 2/15 | 13.3 | 0.44 |
 Antipsychotics | 4/15 | 25.0 | 5/15 | 33.3 | 0.26 |
 Sleep aids | 6/16 | 37.5 | 2/15 | 13.3 | 2.36 |
 Antidepressants | 1/16 | 6.2 | 3/15 | 20.0 | 1.30 |
 Antiepileptic medication | 2/16 | 12.5 | 0/15 | 0.0 | 2.01 |
 | Mean | SD | Mean | SD | t testb |
Age | 7.63 | 2.5 | 8.20 | 2.9 | 0.59 |
Full scale IQ | 86.27 | 21.8 | 87.43 | 11.7 | 0.18 |
Number of concomitant medications per participant | 1.20 | 1.8 | 0.94 | 1.0 | 0.51 |