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Table 1 Demographic data and baseline characteristics

From: A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder

 

Groups

Test of differences

 

NAC

Placebo

 

Characteristics

n/total

%

n/total

%

Chi-squarea

Gender—male

12/16

75.0

12/15

80.0

0.11

Race—White

16/16

100.0

14/15

93.3

1.01

Diagnosis

 Autistic disorder

7/16

43.8

7/15

46.7

0.03

 Asperger’s disorder

2/16

12.5

5/15

33.3

1.92

 PDD-NOS

7/15

43.8

3/15

20.0

1.98

CGI-S

 Marked (5)

6/16

37.5

9/15

60.0

1.57

 Severe (6)

9/16

56.3

6/15

40.0

0.82

 Extreme (7)

1/16

6.3

0/15

0.0

0.97

Concomitant medication (y/n)

6/16

37.5

10/15

66.7

2.64

Medication types

 Psychostimulants

3/16

18.7

3/15

20.0

0.01

 Alpha 2 agonists

1/16

6.2

2/15

13.3

0.44

 Antipsychotics

4/15

25.0

5/15

33.3

0.26

 Sleep aids

6/16

37.5

2/15

13.3

2.36

 Antidepressants

1/16

6.2

3/15

20.0

1.30

 Antiepileptic medication

2/16

12.5

0/15

0.0

2.01

 

Mean

SD

Mean

SD

t testb

Age

7.63

2.5

8.20

2.9

0.59

Full scale IQ

86.27

21.8

87.43

11.7

0.18

Number of concomitant medications per participant

1.20

1.8

0.94

1.0

0.51

  1. aTwo-tailed significance + p < .10; *p < .05. No p values for these chi-squares reached significance at .05 and ranged from .11 to .87
  2. bTwo-tailed significance + p < .10; *p < .05 and ps ranged from .56 to .94
  3. NAC N-acetylcysteine, PDD-NOS pervasive developmental disorder not otherwise specified, CGI-S clinical global impression severity scale