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Fig. 5 | Molecular Autism

Fig. 5

From: Overexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairment

Fig. 5

Viral-mediated overexpression of Homer1a in the BLA impaired fear conditioning: Animals infused with either AAV-Homer1a or AAV-GFP were auditory fear conditioned (AAV-GFP = 6, AAV-Homer1a = 6). a Auditory fear memory assessed 3 h post fear conditioning (i.e., STM) demonstrated significantly reduced freezing in AAV-Homer1a animals. b Auditory fear memory assessed 24 h post fear conditioning (i.e., LTM) demonstrated significantly reduced freezing in AAV Homer1a animals compared to GFP animals. Bars represent the mean ± standard error of the mean (SEM) (*p < 0.05)

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