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Fig. 2 | Molecular Autism

Fig. 2

From: Overexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairment

Fig. 2

Upregulation of BLA Homer1a mRNA in a different cohort of VPA-exposed animals. a Representative picture of before (i) and after (ii) laser microdissection of the BLA tissue. b qRT-PCR for Homer1a revealed an upregulation of Homer1a mRNA in an independent cohort of VPA-exposed animals compared to saline-exposed animals. c qRT-PCR for Homer1, which can identify all isoforms of Homer, did not reveal an overall upregulation of Homer1 in VPA-exposed animals compared to saline animals. d Western blot depicting upregulation of Homer1a (~27 kDa) in VPA-exposed animals compared to saline controls. Bars represent the mean ± standard error of the mean (SEM) (*p < 0.05)

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