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Table 4 Clusters of significant differences in cortical morphometry between TD and ASD

From: Cortical morphological markers in children with autism: a structural magnetic resonance imaging study of thickness, area, volume, and gyrification

Measure Cluster Size (mm2) N vertices p cluster t peak X Tal Y Tal Z Tal Peak region
Age-by-diagnosis interaction effects (df = 97)
 Thickness 1 2965.01 5623 0.0002 4.334 50.3 −56.7 8.2 R middle temporal
  2 2864.20 6405 0.0002 3.867 19.0 −64.6 43.5 R superior parietal
  3 2558.92 6841 0.0005 4.743 14.6 −14.4 37.4 R posterior cingulate
  4 1878.90 3472 0.0080 3.750 26.5 36.7 18.1 R rostral middle frontal
  5 1457.79 2597 0.0375 3.885 −33.0 9.4 28.1 L caudal middle frontal
 Volume 1 2370.44 4619 0.0002 4.677 48.1 −33.0 4.5 R bankssts
  2 1912.43 4245 0.0015 3.658 18.8 −64.9 43.6 R superior parietal
 Gyrification 1 2662.70 6064 0.0001 3.361 −27.8 −49.8 48.5 L superior parietal
  2 4359.25 6920 0.0001 3.277 20.2 58.7 8.9 R rostral middle frontal
  3 2141.64 4528 0.0001 3.243 35.6 8.4 21.8 R pars opercularis
  4 995.32 2324 0.0013 3.586 −17.2 −13.4 57.9 L precentral
  5 824.99 1881 0.0067 3.047 64.9 −20.1 2.4 R superior temporal
Between-group differences (independent of Age) (df = 98)
 Gyrification 1 2275.23 3856 0.0001 3.862 38.9 −78.1 20.8 R inferior parietal
  2 1625.12 2784 0.0001 3.820 51.2 −13.5 −30.5 R inferior temporal
  3 4186.02 7911 0.0001 3.645 −13.5 −48.8 6.2 L isthmus cingulate
  4 1738.54 2122 0.0001 3.644 10.4 −91.7 −1.7 R lingual