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Table 1 Summary of contributing immunological factors in ASC

From: From molecules to neural morphology: understanding neuroinflammation in autism spectrum condition

Level of biological processes Immunological factors involved
Genetic IFN-γ, Toll-like receptors, T-cell receptor
Extracellular mediators Maternal antibodies, cytokines and chemokines
Cell surface proteins Human leukocyte antigen, Toll-like receptors
Intracellular signalling mTOR, PTEN, NF-κB
Neural changes Neuron density, glial proliferation