Skip to main content

Table 2 Global brain volumes of ASD subjects and controls in the entire dataset, in male and female subgroups, and in DD and no-DD male (m) and female (f) subsets

From: The effect of gender on the neuroanatomy of children with autism spectrum disorders: a support vector machine case-control study

Variable (ml)

Subject group, mean ± std

ANOVA

 

ASD (n = 76)

C (n = 76)

ASD vs. C

F

p

GM (ml)

662 ± 67

629 ± 80

7.39

0.007

WM (ml)

424 ± 47

400 ± 55

8.84

0.003

CSF (ml)

225 ± 25

218 ± 34

2.41

0.123

TIV

1310 ± 130

1250 ± 160

7.18

0.008

 

ASDm (n = 38)

ASDf (n = 38)

Cm (n = 38)

Cf (n = 38)

ASDm vs. Cm

ASDf vs. Cf

F

p

F

p

GM (ml)

699 ± 62

625 ± 48

664 ± 83

594 ± 60

4.25

0.043

5.90

0.018

WM (ml)

449 ± 43

400 ± 38

422 ± 56

376 ± 44

5.38

0.023

5.93

0.017

CSF (ml)

238 ± 25

212 ± 17

232 ± 38

203 ± 19

0.52

0.470

5.08

0.027

TIV (ml)

1390 ± 120

1240 ± 100

1320 ± 170

1170 ± 120

3.90

0.052

6.13

0.016

 

ASD-DDm (n = 19)

ASD-noDDm (n = 19)

ASD-DDf (n = 19)

ASD-noDDf (n = 19)

C-DDm (n = 19)

C-no-DDm (n = 19)

C-DDf (n = 19)

C-no-DDf (n = 19)

ASD-DDm vs. C-DDm

ASD-noDDm vs. C-noDDm

ASD-DDf vs. C-DDf

ASD-noDDf vs. C-noDDf

F

p

F

p

F

p

F

p

GM (ml)

702 ± 85

696 ± 65

616 ± 59

633 ± 35

661 ± 85

668 ± 83

584 ± 53

605 ± 66

2.98

0.09

1.34

0.255

3.21

0.081

2.73

0.107

WM (ml)

453 ± 44

445 ± 43

393 ± 44

406 ± 31

424 ± 62

421 ± 51

369 ± 41

384 ± 47

2.72

0.108

2.55

0.119

3.04

0.090

2.90

0.097

CSF (ml)

238 ± 31

238 ± 28

211 ± 20

213 ± 13

228 ± 31

236 ± 44

200 ± 16

206 ± 22

1.13

0.294

0.01

0.906

3.54

0.068

1.65

0.207

TIV (ml)

1390 ± 210

1380 ± 130

1220 ± 120

1250 ± 70

1310 ± 170

1330 ± 170

1150 ± 110

1200 ± 130

2.71

0.109

1.24

0.272

3.37

0.075

2.78

0.104

  1. Abbreviations: ASD autism spectrum disorder, C controls, ASDm ASD males, Cm control males, ASDf ASD females, Cf control females, ASD-DDm ASD males with developmental delay, C-DDm control males with developmental delay, ASD-noDDm ASD males without developmental delay, C-noDDm control males without developmental delay, ASD-DDf ASD females with developmental delay, C-DDf control females with developmental delay, ASD-noDDf ASD females without developmental delay, C-noDDf control females without developmental delay, GM grey matter, WM white matter, CSF cerebrospinal fluid, TIV total intracranial volume, std standard deviation
Back to article page

Molecular Autism

ISSN: 2040-2392