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Table 2 Group differences in fMRI BOLD activation for ToM vs. random animation and GD vs. random animation (whole-brain analysis)

From: Aberrant functioning of the theory-of-mind network in children and adolescents with autism

Contrast and direction

Region

Hemi.

Cluster vol. (in μl)

Peak coordinates MNI

Peak

x

y

z

t

ToM vs. RD

Superior medial gyrus

L

28,593

−4

36

34

5.0

TD > ASD

Insula/inferior frontal

L

7371

−24

22

−12

4.1

 

Precentral gyrus

L

6453

−40

4

34

5.0

 

Angular gyrus

L

5427

−42

−56

40

4.0

 

Cerebellum (Crus VI)

L

3213

−22

−86

−26

4.8

 

Precuneus

L

3024

−6

−44

40

3.7

 

Thalamus

R

2835

2

−8

18

4.3

ASD > TD

N/A

N/A

N/A

N/A

N/A

N/A

N/A

GD vs. RD

       

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

  1. L left, R right, Hemi. hemisphere, vol. volume