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Fig. 2 | Molecular Autism

Fig. 2

From: Platelet studies in autism spectrum disorder patients and first-degree relatives

Fig. 2

Aggregation responses following platelet activation with epinephrine in ASD patients, siblings, parents, and adult controls. a Schematic representation of platelet aggregation curve induced by 1.25 μg/mL epinephrine showing monophasic (1 wave), biphasic (2 waves), or delayed biphasic aggregation curves. Graphs indicating gender-corrected least squares means and 95 % CI values based on the linear mixed model analysis of maximal aggregation amplitude in response to b 2.5 μg/mL epinephrine and c 1.25 μg/mL epinephrine measured in 159 ASD patients, 103 siblings, 186 parents, and 45 adult controls measured in platelet-rich plasma. Tukey-Kramer-adjusted p values of the pairwise comparisons in four groups are indicated when they are significant (p < 0.05). Graphs indicating percentage of individuals per group with either normal, delayed, or absent secondary wave aggregation following d 2.5 μg/mL epinephrine, or e 1.25 μg/mL epinephrine

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