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Fig 6 | Molecular Autism

Fig 6

From: Role of the cytoplasmic isoform of RBFOX1/A2BP1 in establishing the architecture of the developing cerebral cortex

Fig 6

Role of mRbfox1-iso2 in the dendrite growth in cortical neurons in vivo. a pCAG-loxP-GFP was electroporated for sparse expression with pCAG-M-Cre together with pSuper vector (Control) or pSuper-mRbfox1-iso2 (iso2) at E14.5. Analyses were carried out in cortical slices at P30. Representative average Z-stack projection images of GFP fluorescence of upper layer cortical neurons were shown. b, c One section from each brain was analyzed for control (n = 4) and iso2 (n = 6) experiments. Representative data were shown. b Total dendritic length was calculated for neurons observed at P30. Error bars indicate SD; **p < 0.01 by Student’s t test. c Branch points of dendrites were analyzed by Sholl test. Error bars indicate SD (n = 19 neurons for control, n = 20 for iso2); **p < 0.01 by Tukey-Kramer LSD.

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Molecular Autism

ISSN: 2040-2392