Fig. 3

Role of mRbfox1-iso2 in the terminal translocation of cortical neurons. a mRbfox1-iso2-knockdown hampers the terminal translocation. Cerebral cortices were electroporated with pCAG-EGFP together with pSuper vector (control) or pSuper-mRbfox1-iso2 (iso2) at E15.5. Coronal sections were prepared at P3 and immunostained with anti-GFP (white) and DAPI (blue). Dotted lines represent the pial surface (upper) and top of CP (lower). MZ marginal zone, PCZ primitive cortical zone. b Statistical analyses of a. Distance between the top of CP and the cell soma was measured. Representative slices form 5 (control) or 4 (iso2) brains were analyzed for each analysis. Numbers of cells used for each calculation were 100. Error bars indicate SD; **p < 0.01 by Student’s t test