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Fig. 4 | Molecular Autism

Fig. 4

From: CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment

Fig. 4

Difference in gene length between DEGs and non-DEGs. Plotted here are length distributions of genes with CHD8 binding in NPCs (a), without CHD8 binding in NPCs (b), and all genes in neurons (c). In NPCs, mean of gene lengths is 117 kb for DEG and 76 kb for non-DEG; in neurons, mean of gene lengths is 98 kb for DEGs and 74 kb for non-DEGs, whereas gene lengths were defined as the distances from transcription start site to termination site in Gencode v18. *p < 0.01, **p < 1e-5, ***p < 1e-9, t test, two-tailed

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Molecular Autism

ISSN: 2040-2392