Fig. 3

Cortico-subcortical correlational analysis. Subcortical-cortico correlational analysis showing the relationship between IS severity and Region X Region structural covariance (a), as measured by a single-subject covariance analog (see “Statistical analysis” section). Cortical regions are ordered by hemisphere ¹ and FDR cutoff is indicated by **. Relationships that survive FDR correction are highlighted by making non-significant differences partially transparent. See Additional file 8: Table S2 for exact r and p values for significant relationships. b shows a subset of these significant relationships: cortical regions whose relationship with the putamen (red), amygdala (blue), or both (purple) significantly related to IS severity