Targeted massively parallel sequencing of autism spectrum disorder-associated genes in a case control cohort reveals rare loss-of-function risk variants

Table 1 Categories of coding variation per individual

	Cases	Controls
Total variants	23,756 ± 836	23,749 ± 797
Coding	765 ± 62	760 ± 64
Missense	307 ± 30	305 ± 31
Damaging	85 ± 12	84 ± 13
Nonsense/splice (loss-of-function)	3 ± 1.4	2.5 ± 1.8

All coding variant passing quality control filters were annotated and categorized by ANNOVAR into these categories

ISSN: 2040-2392