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Table 1 Spine/filopodia and filopodia/spine ratios of rat primary hippocampal neurons overexpressing different SHANK3 variants

From: Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID

Fusion protein Spines/filopodia Filopodia/spines
Control 2.70 0.37
SHANK3 2.15 0.47
G1527A 1.32 0.76
2497delG 0.94 1.07
A5008T 3.26 0.31