Table 1 Top five SNPs from tier 1 analysis: unique to chromosome X in regions that escape X-inactivation
From: The female protective effect in autism spectrum disorder is not mediated by a single genetic locus
AGRE discovery (208 cases, 151 controls) | SSC replication (207 cases, 676 controls) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
SNP | Allele 1/allele 2 | Affected allele 1 frequency (%) | Unaffected allele 1 frequency (%) | Odds ratio | P value | Corrected P value | Affected allele 1 frequency (%) | Unaffected allele 1 frequency (%) | Odds ratio | P value |
Predicted | . | 97.0 | <24.3 | >88 | ≤1×10−8 | ≤0.05 | 97.0 | <24.3 | >88 | ≤1×10−8 |
rs5913021 | G/A | 71.5 | 57.3 | 1.25 | 0.005 | 1.0 | . | . | . | . |
rs5913336 | A/G | 49.0 | 63.6 | 0.77 | 0.006 | 1.0 | 69.6 | 60.9 | 1.14 | 0.007 |
rs5912329 | A/G | 71.4 | 58.2 | 1.23 | 0.01 | 1.0 | . | . | . | . |
rs1395790 | G/A | 2.4 | 7.9 | 0.30 | 0.01 | 1.0 | . | . | . | . |
rs6624177 | A/G | 60.0 | 72.2 | 0.83 | 0.02 | 1.0 | . | . | . | . |