Effects of autism spectrum disorders on outcome in teenage-onset anorexia nervosa evaluated by the Morgan-Russell outcome assessment schedule: a controlled community-based study

Table 6 Morgan-Russell subscale E2 (emancipation from family); dose–response analysis

Dose	AN study 2				AN study 3				AN study 4				Analysis for time trend doubly ordered r × c contingency tables Linear-by-linear association test	Exact Monte Carlo
	Response category				Response category				Response category				Test statistic	P (99% CI)
	0	4	8	12	0	4	8	12	0	4	8	12
Never ASD	2	5	8	19	2	2	7	23	0	1	5	28	+2.562	0.01 (0.008 to 0.014)
ASD × 1-3	0	2	0	8	0	1	1	8	0	1	2	7	0	1 (0.9995 to 1)
ASD × 4	1	2	0	3	0	2	1	3	2	1	2	1	−0.743	0.54 (0.53 to 0.56)
Dose–response analysis doubly ordered r × c contingency tables	Linear-by-linear association test				Linear-by-linear association test				Linear-by-linear association test				Stratified r × c contingency tables Cochran-Mantel-Haenszel test
Test statistic	−0.541				−0.483				−3.814				−2.606
Exact Monte Carlo P	0.6				0.72				0.0005				0.01
99% CI	0.59 to 0.62				0.71 to 0.74				0 to 0.001				0.008 to 0.013

AN anorexia nervosa, AN study 2 second anorexia nervosa examination, AN study 3 third anorexia nervosa examination, AN study 4 fourth anorexia nervosa examination, ASD autism spectrum disorders, never ASD individuals who had never been assigned an ASD diagnosis, ASD × 1–3 those who had been assigned an ASD diagnosis in at least one study, but not at all four studies, ASD × 4 those with an ASD diagnosis at all four examinations, CI confidence interval, r × c rows and columns.

ISSN: 2040-2392