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Table 2 Efficacy table

From: A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism

  Change from baseline Omega-3 change - placebo change P value
Omega-3 Placebo   
PDDBI (negative change is an improvement)     
   Autism composite −4.5 (−8.5; −0.6) −6.4 (−10.2; −2.7) 1.9 (−3.3;7.0) 0.5
  Sensory perception −2.0 (−5.0; 1.1) −3.7 (−6.7; −0.6) 1.7 (−2.4;5.9) 0.4
  Social pragmatic −0.9 (−5.4; 3.5) −4.3 (−8.6; 0.1) 3.3 (−2.7;9.3) 0.3
  Semantic pragmatic −0.4 (−5.1; 4.2) −1.7 (−6.3; 2.9) 1.2 (−5.2;7.6) 0.7
  Social approacha −3.3 (−7.4; 0.8) −1.8 (−5.6; 2.0) −1.5 (−6.9;3.9) 0.6
  Expressive languagea −3.5 (−7.3; 0.2) −1.5 (−5.0; 2.1) −2.1 (−7.1;3.0) 0.4
  Ritualism/Resistance to change −3.8 (−6.8; −0.9) −6.4 (−9.3; −3.5) 2.6 (−1.5;6.6) 0.2
BASC (negative change is an improvement)     
  Internalizing 2.2 (−2.1; 6.6) −2.6 (−6.9; 1.7) 4.8 (−1.0;10.6) 0.1
   Externalizing 3.2 (−0.5; 6.9) −3.0 (−6.6; 0.6) 6.2 (1.3;11.2) 0.02 a
  Functional communicationa −0.3 (−3.9; 3.3) −4.3 (−7.8; −0.8) 4.0 (−0.9;8.9) 0.1
  Sociala −1.2 (−4.2; 1.9) −4.6 (−7.5; −1.7) 3.4 (−0.6;7.4) 0.1
VABS (positive change is an improvement)     
   Adaptive functioning composite 2.8 (0.2; 5.3) −0.2 (−2.6; 2.2) 3.0 (−0.4;6.4) 0.09
  Motor 0.4 (−4.5; 5.4) −1.9 (−6.6; 2.9) 2.3 (−4.5;9.1) 0.5
  Social −0.3 (−3.1; 2.5) 0.8 (−1.8; 3.4) −1.1 (−4.8;2.6) 0.6
  Communication 1.6 (−1.5; 4.7) 0.9 (−2.0; 3.9) 0.6 (−3.5;4.8) 0.8
  Daily living 5.5 (0.9; 10.0) −0.7 (−5.0; 3.6) 6.2 (0.01;12.3) 0.05
PLS (positive change is an improvement)     
   Total language score 0.7 (−2.7; 4.1) −0.6 (−3.7; 2.6) 1.3 (−3.1;5.7) 0.6
  1. Primary/secondary outcome measures are in italics. All other measures are considered exploratory.
  2. aItems are reversed so that negative change corresponds to an improvement across all PDDBI and BASC items.