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Table 3 Results of SNP association analyses in our sample and in the PGC database

From: Genetic variant rs17225178 in the ARNT2 gene is associated with Asperger Syndrome

SNP ID

MAF (cases)

MAF (controls)

SNP association analysis in our sample

SNP association analysis in the PGC database

OR

X 2

P value

OR

SE

P value

rs3848173

0.2288

0.1667

1.484

4.768

0.029

   

rs17225178

0.1966

0.1173

1.842

9.773

0.001771

1.115

0.0433

0.0121

  1. Nominally significant P values after genetic association analysis between 34 SNPs in ARNT2 and AS in our sample are reported (α = 0.05). Significant P value after Bonferroni correction for total number of SNPs is written in bold and italicized (α = 0.0024). Major allele is the reference allele for the estimated OR. Results of genetic association analysis between rs17225178 and ASC in the PGC database are also reported. AS, Asperger Syndrome; ASC, Autism Spectrum Conditions; MAF, minor allele frequency; OR, odds ratio; PGC, Psychiatric Genomics Consortium; SE, standard error for the odds ratio; SNP, single nucleotide polymorphism.