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Table 3 Estimated diagnosis and sex differences for diffusion measures

From: Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder

  Diagnosis differences by sex Sex difference by diagnosis
  Males: ASD vs. TD Females: ASD vs. TD ASD: males vs. females TD: males vs. females
  Estimate (SE) P value Estimate (SE) P value Estimate (SE) P value Estimate (SE) P value
Diffusion parameter
 Mean diffusivity (10−5 mm2/s) −0.30 (0.88) 0.74 4.14 (1.41) 0.003 −3.51 (1.13) 0.002 0.92 (1.22) 0.45
 Axial diffusivity (10−5 mm2/s) −0.55 (1.01) 0.59 4.44 (1.62) 0.006 −3.09 (1.30) 0.02 1.90 (1.40) 0.17
 Radial diffusivity (10−5 mm2/s) −0.15 (0.99) 0.88 4.04 (1.58) 0.01 −3.76 (1.27) 0.003 0.42 (1.37) 0.76
  1. Parameter estimates and standard errors are from the mixed-effects models assessing the relationship of diagnostic group, age, cortical projection zone subregions, and sex with diffusion measures. The reported models included fixed effects for scanner upgrade, diagnosis, sex, age, subregion, and the interactions between diagnosis and sex and between age and subregion. Random effects for person and region were included to account for the repeated measures. Models also included and tested other two-way interactions, but none were significant and were not retained in the reported model.