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Figure 4 | Molecular Autism

Figure 4

From: Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin

Figure 4

Developmental profile of Tph2 -/- mouse pups at postnatal days (PND) 3, 6, and 9. (A) Body temperature in degrees Celsius (°C) and (B) body weight in grams (g) in pups tested for isolation-induced ultrasonic vocalizations. Black circles: Tph2 wildtype (Tph2 +/+) control mice; grey circles: Tph2 heterozygous (Tph2 +/-) mice; white circles: Tph2 null mutant (Tph2 -/-) mice. Data are presented as means ± standard errors of the mean. **P < .005 Tph2 +/+ vs. Tph2 -/-; ***P < .001 Tph2 +/+ vs. Tph2 -/-; ## P < .005 Tph2 +/- vs. Tph2 -/-; ### P < .001 Tph2 +/- vs. Tph2 -/-. Please note that the error bars in B are too small to be visible.

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