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Table 1 Group differences in lateralization for various subject inclusion criteria

From: Abnormal lateralization of functional connectivity between language and default mode regions in autism

Inclusioncriteria

Total n (Autism n)

Region of interest 1

Region of interest 2

t

P

A

964 (447)

Posterior cingulate

Wernicke

3.37

7.7 × 10-4

  

Posterior cingulate

Broca

3.04

2.4 × 10-3

  

Temporoparietal junction

Wernicke

3.63

2.9 × 10-4

B

831 (362)

Posterior cingulate

Wernicke

3.39

7.2 × 10-4

  

Posterior cingulate

Lateral premotor

2.93

3.5 × 10-3

  

Temporoparietal junction

Wernicke

3.66

2.7 × 10-4

C

765 (447)

Posterior cingulate

Wernicke

3.69

2.4 × 10-4

  

Posterior cingulate

Broca

3.52

4.6 × 10-4

  

Posterior cingulate

Lateral premotor

3.63

3.0 × 10-4

  

Posterior cingulate

Left supplementary motor area

2.74

6.3 × 10-3

  

Temporoparietal junction

Wernicke

3.78

1.6 × 10-4

  

Temporoparietal junction

Left supplementary motor area

2.87

4.2 × 10-3

D

645 (362)

Posterior cingulate

Wernicke

3.83

1.4 × 10-4

  

Posterior cingulate

Lateral premotor

3.79

1.7 × 10-4

  

Temporoparietal junction

Wernicke

3.71

2.3 × 10-4

E

850 (378)

Temporoparietal junction

Wernicke

3.33

8.9 × 10-4

F

822 (396)

Posterior cingulate

Wernicke

3.36

8.3 × 10-4

  

Temporoparietal junction

Wernicke

3.30

1.0 × 10-3

G

765 (280)

Posterior cingulate

Wernicke

3.30

1.0 × 10-3

  

Posterior cingulate

Broca

2.93

3.5 × 10-3

  

Temporoparietal junction

Wernicke

3.04

2.4 × 10-3

  

Medial prefrontal

Wernicke

2.74

6.2 × 10-3

  

Posterior cingulate

Lateral premotor

3.36

8.3 × 10-4

H

610 (309)

Temporoparietal junction

Wernicke

3.22

1.3 × 10-3

  1. A: Met all preprocessing criteria (described in Methods section) and part of site with >20 subjects.
  2. B: Criteria A + subject has >50% resting state BOLD volumes after motion scrubbing.
  3. C: Criteria A + subject not included in 1000 Functional Connectomes or ADHD200 datasets.
  4. D: Criteria A + B + C.
  5. E: Criteria A + right-handed subjects only.
  6. F: Criteria A + male subjects only.
  7. G: Criteria A + autism only (that is, removed individuals with Asperger’s syndrome and Pervasive Developmental Disorder- Not Otherwise Specified (PDD-NOS). H: Criteria A + matched groups on verbal IQ (80 < autism verbal IQ <130 and 70 < control verbal IQ <120).