Association study between autistic-like traits and polymorphisms in the autism candidate regions RELN, CNTNAP2, SHANK3, and CDH9/10

Table 2 ASD ^a case–control analyses

Gene	SNP	Genotype	N (case/control)	P value^b	OR (CI 95%)
CDH 9/10	rs4307059	C/C	12/1,651	0.835	1.087 (0.541-2.184)
		T/C	37/5,527		1.160 (0.714-1.884)
		T/T	36/4,730
CNTNAP2	rs2710102	A/A	25/3,223	0.800	0.806 (0.419-1.551)
		A/G	44/5,932		0.846 (0.468-1.529)
		G/G	17/2,735
CNTNAP2	rs7794745	A/A	41/4,963	0.125	0.351 (0.127-0.972)
		T/A	40/5,493		0.422 (0.152-1.168)
		T/T	5/1,559
RELN	rs362691	C/C + C/G	20/2,820	0.933	1.023 (0.601-1.742)
		G/G	63/9,076
SHANK3	rs9616915	C/C	30/3,086	0.094	0.764 (0.425-1.373)
		T/C	31/5,808		1.371 (0.769-2.447)
		T/T	21/2,906

^aAbove the score 8.5 on A-TAC.
^bUncorrected P value.
ASD: Autism spectrum disorder; A-TAC: Autism-Tics, ADHD, and Other Co-morbidities inventory.

ISSN: 2040-2392