Identification of rare DNA sequence variants in high-risk autism families and their prevalence in a large case/control population

Table 2 Chromosomal regions selected for sequencing based on haplotype sharing

Eighteen shared haplotype regions	Chromosome	Location (hg18)	Location (hg19)	Affecteds sharing haplotype
2p14-p12	2	65612029-76349401	65758525-76495893	6 of 6
2q23-q31	2	153638312-174296304	153930066-174588058	6 of 6
2q37	2	231435643-238617145	231727399-238952406	5 of 7
3q13	3	111604019-112685490	110121329-111202800	4 of 7
3q26-q27	3	174594938-185701563	173112244-184218869	4 of 7, 4 of 4
4q28-q31	4	137362554-141629142	137143104-141409692	6 of 6
7p21	7	7381742-11861952	7415217-11895427	4 of 4, 4 of 6
7p14	7	36090817-41521542	36124292-41555017	4 of 7
7q21-q31	7	90511244-107823133	90673308-108035897	5 of 8^a
7q35-36	7	142750349-151152511	143040227-151521578	4 of 6
12q21	12	76119990-77788028	77595859-79263897	5 of 7
12q21	12	79689788-87939487	81165657-89415356	5 of 8
14q11-q21	14	22912579-45661808	23842739-46592058	3 of 4, 6 of 6
14q32	14	92331535-103509782	93261782-104440029	4 of 4
15q12-q21	15	24339787-43759484	26788694-45972192	3 of 4, 4 of 6, 5 of 8
16q22-23	16	73415053-77780513	74857552-79223012	4 of 7, 5 of 6, 3 of 4
20p11-q13	20	25253250-41225971	25305250-41792557	4 of 7
20q13	20	49062886-57757418	49629479-58324023	5 of 6, 5 of 6

Where multiple numbers are given, multiple families shared overlapping haplotypes. ^aIndicates a family where a ninth affected individual was later shown not to share the same haplotype.

ISSN: 2040-2392