Co-segregation of a RAB11FIP5 variant. Two-generation pedigree (pedigree 1) with three male siblings affected with autism. Sequence variants identified in the family are shown in the black boxes. Open boxes - unaffected male family members; open circles - unaffected female family members; filled boxes - affected male family members. Odds ratios for the variants observed in the case/control study are shown. Variants with no odds ratio were observed only in high-risk families. All family members were tested for all variants.