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Table 1 Demographic characteristics of postmortem brain samples

From: Dysregulation of estrogen receptor beta (ERβ), aromatase (CYP19A1), and ER co-activators in the middle frontal gyrus of autism spectrum disorder subjects

Variable Control ASD
Age (years) 11.70 ± 1.584 11.80 ± 1.609
PMI (h) 14.46 ± 2.171 19.00 ± 2.776
Sex (F/M) 1/12 0/13
Storage (days) 4287 ± 638.7 2829 ± 397.7
RIN 5.55 ± 0.71 6.84 ± 0.53
pH 5.95 ± 0.06 6.11 ± 0.07
Manner of death Drowning (3), Vehicle accident (4), Hanging/suicide (2), Cardiovascular complication (1), TSS (1), Multisystem failure (1), Anaphylaxis (1) Drowning (6)
Vehicle accident (1)
Cardiovascular complication (2)
Cancer (1)
Hemorrhage (2)
Diabetic ketoacidosis (1)
Medications* Yes (1) (Concerta, Clonidine) Yes (4) (Zyprexa (1), Reminyl (1), Naltrexone (1), Risperdal (2), Luvox (1), Clonidine (1), Insulin (1))
No (12)
No (9)
  1. ASD, Autism spectrum disorder; F, Female; M, Male; PMI, Postmortem interval; RIN, RNA integrity; TSS, Toxic shock syndrome. Values are Mean ± SE. *Note that some individuals took multiple medications.