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Table 1 Summary of metabolic findings in patient MT (Asperger’s) and PL (PDD-NOS)

From: Autism spectrum disorder associated with low serotonin in CSF and mutations in the SLC29A4 plasma membrane monoamine transporter (PMAT) gene

Patient Age (years) 5HIAA (nmol/L) HVA (nmol/L) HVA/5HIAA (ratio) Serotonin
      Blood (ng/mL) Platelets (ng/×109)
MT 9.6 64.7 389.6 6.0 287 1041
PL 6.2 73.6 399.8 5.4 221 675
Ref* 5–10* 133 (88–178)* 523 (144–801)* 1.5–3.5* 50–220** 125–500**
  1. HVA, homovanillic acid; 5HIAA, 5-hydroxyindolacetic acid (serotonin end-metabolite).
  2. *Reference values and ranges see ref. [33].
  3. **Reference values see ref. [34].