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Table 1 Single SNP association analyses

From: Single nucleotide polymorphism rs6716901 in SLC25A12 gene is associated with Asperger syndrome

dbSNp ID

Allelesa

MAFb

Odds ratio

Confidence interval

F_Acc

F_Ud

Chi-sqe

P-valuef

Alphag

rs6716901

G/A

0.13

1.70

0.98 to 3.02

0.18

0.11

6.87

0.008

0.016

rs2056202

C/T

0.13

0.76

0.39 to 1.46

0.10

0.13

1.29

0.26

0.016

rs3765166

G/A

0.23

1.31

0.81 to 2.07

0.27

0.22

2.51

0.11

0.016

  1. Significant P-values are written in italics. MAF, minor allele frequency.
  2. acommon allele is listed first.
  3. bcalculated by Plink v1.07 in analysed sample.
  4. cthe frequency of the minor allele in cases.
  5. dthe frequency of the minor allele in controls.
  6. ethe chi-squared statistic for this test (1 df).
  7. fcomputed on the basis of likelihood ratio test.
  8. gdetermined after evaluating the number of completely independent SNPs using SNPSpD.
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Molecular Autism

ISSN: 2040-2392