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Table 2 Top-ranked biological functions enriched in probes differentially expressed (P < 0.01) from IPA

From: Transcriptomic changes in the frontal cortex associated with paternal age

Biological function P value
Maturation of dendritic cells 8.99 × 10-5
Influx of phagocytes 1.69 × 10-4
Binding of interferon-stimulated response element 6.43 × 10-4
Damage of oligodendrocytes 7.00 × 10-4
Lack of mesenteric lymph node 7.00 × 10-4
Lack of peripheral lymph node 7.00 × 10-4
Stimulation of hyaluronic acid 7.00 × 10-4
Morphology of tooth 7.56 × 10-4
Activation of myeloid cells 7.78 × 10-4
Clustering of lymph node cells 1.16 × 10-3
Osteoclastogenesis of bone cell lines 1.16 × 10-3
Transmigration of Th1 cells 1.16 × 10-3
Influx of neutrophils 1.21 × 10-3
Proliferation of dendritic cells 1.27 × 10-3
Destruction of joint 1.47 × 10-3
Arrest in cell cycle progression of endothelial cells 1.73 × 10-3
Lack of cervical lymph node 1.73 × 10-3
Organogenesis of lymphoid organ 1.73 × 10-3
Response of carcinoma cell lines 1.73 × 10-3
Extravasation of myeloid cells 1.92 × 10-3
Morphogenesis of neurites 1.97 × 10-3
Induction of neuroglia 2.40 × 10-3
Quantity of IL-5 In blood 2.40 × 10-3
Quantity of multinucleated cells 2.40 × 10-3
Response of lung cancer cell lines 2.40 × 10-3
Activation of monocytes 2.45 × 10-3
Acne 2.48 × 10-3
Formation of osteoclasts 2.60 × 10-3
Mobilization of blood cells 2.63 × 10-3
Activation of phagocytes 2.69 × 10-3
Binding of lymphoma cell lines 2.76 × 10-3
Cell viability of blood cells 2.82 × 10-3
Quantity of tooth 3.17 × 10-3
Activation of macrophages 3.23 × 10-3
Proliferation of B lymphocytes 3.35 × 10-3
Response of connective tissue cells 3.42 × 10-3
Cell movement of dendritic cells 3.88 × 10-3