Table 1 Probes showing gene expression differences associated with paternal age ( P < 0.001)
From: Transcriptomic changes in the frontal cortex associated with paternal age
Transcript | Probe ID | Expression differencea | P value | Mean (SEM) young | Mean (SEM) old |
|---|---|---|---|---|---|
AA408296 | 4150356 | ↑ | 3.23 × 10-6 | 6.62 (0.01) | 6.71 (0.01) |
Muc15 | 2120176 | ↓ | 7.45 × 10-6 | 6.5 (0.01) | 6.42 (0.01) |
Lta | 2900474 | ↑ | 7.46 × 10-6 | 6.52 (0.01) | 6.61 (0.01) |
Tslp | 6960520 | ↑ | 3.02 × 10-5 | 6.41 (0.01) | 6.48 (0.01) |
Zfp35 | 580168 | ↓ | 1.30 × 10-4 | 6.99 (0.02) | 6.89 (0.01) |
Gstm1 | 4540458 | ↑ | 1.31 × 10-4 | 6.57 (0.02) | 6.66 (0.01) |
Rdh20 | 6840020 | ↑ | 1.38 × 10-4 | 6.48 (0.01) | 6.56 (0.01) |
Ccdc90b | 6100215 | ↑ | 1.91 × 10-4 | 7.1 (0.02) | 7.22 (0.02) |
Sdhc | 3290630 | ↓ | 2.10 × 10-4 | 6.48 (0.01) | 6.4 (0.02) |
Atp5sl | 5270131 | ↓ | 2.97 × 10-4 | 7.76 (0.02) | 7.61 (0.03) |
Olfr187 | 380370 | ↓ | 3.07 × 10-4 | 6.59 (0.01) | 6.51 (0.01) |
Cd44 | 4880138 | ↓ | 3.29 × 10-4 | 6.64 (0.01) | 6.57 (0.01) |
Fryl | 510059 | ↑ | 3.58 × 10-4 | 6.57 (0.01) | 6.64 (0.01) |
Accn1 | 7330561 | ↑ | 3.59 × 10-4 | 6.69 (0.01) | 6.76 (0.01) |
Cd177 | 670452 | ↓ | 3.71 × 10-4 | 6.51 (0.01) | 6.43 (0.01) |
Tspan3 | 3130497 | ↑ | 3.96 × 10-4 | 10.33 (0.04) | 10.49 (0.03) |
Olfr92 | 2710201 | ↑ | 4.29 × 10-4 | 6.47 (0.01) | 6.53 (0.01) |
Shh | 2260450 | ↑ | 4.37 × 10-4 | 6.71 (0.02) | 6.79 (0.01) |
E130303B06RIK | 6250669 | ↓ | 4.38 × 10-4 | 6.67 (0.01) | 6.59 (0.01) |
Arhgap6 | 7550333 | ↓ | 4.43 × 10-4 | 6.45 (0.01) | 6.39 (0.01) |
Zc3h18 | 7380382 | ↑ | 5.21 × 10-4 | 7 (0.01) | 7.08 (0.02) |
Atg5 | 3850450 | ↓ | 6.10 × 10-4 | 7.98 (0.02) | 7.9 (0.01) |
Nsfl1c | 7610433 | ↓ | 7.45 × 10-4 | 7.69 (0.02) | 7.55 (0.03) |
Ear12 | 4540543 | ↓ | 7.47 × 10-4 | 6.52 (0.01) | 6.46 (0.01) |
Olfr1366 | 6860093 | ↓ | 7.69 × 10-4 | 6.49 (0.02) | 6.41 (0.01) |
Tnfsf11 | 2480255 | ↑ | 8.20 × 10-4 | 6.5 (0.01) | 6.57 (0.01) |
Lcorl | 2470343 | ↓ | 8.27 × 10-4 | 6.56 (0.01) | 6.49 (0.01) |
Dus1l | 2370138 | ↑ | 9.30 × 10-4 | 7.13 (0.01) | 7.21 (0.02) |
Larp4 | 6400025 | ↓ | 9.59 × 10-4 | 6.47 (0.01) | 6.41 (0.01) |
Alg12 | 3850500 | ↑ | 9.79 × 10-4 | 6.56 (0.01) | 6.65 (0.02) |
Ier5l | 4900053 | ↓ | 9.82 × 10-4 | 7.6 (0.02) | 7.47 (0.03) |
Ccl26 | 4560164 | ↓ | 9.94 × 10-4 | 6.49 (0.01) | 6.41 (0.02) |