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Table 1 List of genes predicted to affect risk for ASD (rASD genes)

From: DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics

   Range of FDRq-values
Number of dnLoF mutations 0-0.0025 0.0025-0.025 0.025-0.05
>1 CUL3, DYRK1A, dGRIN2B, a,d   
  POGZ, SCN2A, aTBR1a,d   
1 ADNP, dCBX4, CDC42BPB, ARID1B, dATP1B1, BCL11A, RIMS1 e
  COL25A1, DIP2C, DDX3X, CSTF2T, FOXP1, bITGA5,  
  LMTK3, MED13L, NFIA, L1CAM, cNCKAP1, MBD5,a  
  RAB2A, PHF2, RNF38, PCOLCE, SCP2, SHANK2, a  
  PPM1D, PRPF39, SETBP1, SPAST, SMARCC2, TCF3,  
  TROVE2, UBR3, ZMYM2 UNC80, VCP  
0 BANK1, C1orf95, ELOVL1, AGK, ARSK, ATRN, BBS10, b ACTL6A, ANKS1B, ASB8,
  FCAR, LMCD1, SMC3, BEND7, C2CD3, CD34, BAHCC1, C1orf43,
  PRIM2, PTEN, c,dSERINC5, CHMP2B, CLDN11, CNOT1, CASD1, CDC42EP4, DUSP14,
  SMAP1, TNC, CRY1, DCAF11, DHX29, HCFC2, HIST1H3D, LYSMD3,
  ZNF175, ZNF33A DYNC1I2, EIF3G, F3, FBXL5, MARK4, NAV2, PAMR1,
   GDPD4, GMNN, HIST1H4B, PCNX, PSMG2, RSU1,
   KIAA1468, ITGB3BP, MAPK4, SMPD3, SPRY1, TNPO3,
   MCM5, MAPT, MARCO, VASH1, ZNF410
   METTL14, MRPS26, MRPL44,  
   MUDENG, NCOR1, NDUFB5,  
   NIF3L1, NR2F1, OR2AK2,  
   PCIF1, PDLIM1, RAD21,  
   RAD51AP1, RBBP9, REXO1,  
   RNF168, SCD, SLC22A15,  
   SMG7, SPAG17, STXBP1, c  
   TBL1XR1, dTSR1, ZFAND2A  
  1. *ASD genes are displayed by range of False Discovery Rate (FDR) q-value; the 3 columns correspond to genes significant with a genome-wide correction at levels.0025,.025, and.05, respectively. Genes with FDR <.05, but validation score less than.90 were not included. agene with strong prior support for affecting risk for ASD; bgene with modest prior support for affecting risk for ASD; csyndromic gene; dgene with a de novo loss-of-function mutation in the [17] study; eRIMS1 has one de novo loss-of-function mutation, netscore = 107 (95th percentile), and FDR of.077 exceeding the cutoff.