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Table 2 The results of the five-way mixed-design repeated-measurement ANOVA, with the between-subject factor as Group (ASD and NT) and Measure (SCR and PPG) and the within-subject factors as Medication (oxytocin and placebo), Source (human and non-human sound), and Pleasantness (pleasant and unpleasant sound), performed to evaluate the effect of oxytocin inhalation on the autonomic responses

From: The effect of intranasal oxytocin versus placebo treatment on the autonomic responses to human sounds in autism: a single-blind, randomized, placebo-controlled, crossover design study

 

df

F

p

Group

1, 112

2.349

0.128

Measure

1, 112

18.718

0.000***

Group *Measure

1, 112

4.177

0.043*

Medication

1, 112

0.790

0.376

Medication *Group

1, 112

7.000

0.009**

Medication *Measure

1, 112

1.553

0.215

Medication *Group *Measure

1, 112

7.080

0.009**

Source

1, 112

0.458

0.500

Source *Group

1, 112

0.951

0.332

Source *Measure

1, 112

0.144

0.705

Source *Group *Measure

1, 112

0.701

0.404

Pleasantness

1, 112

2.194

0.141

Pleasantness *Group

1, 112

0.133

0.716

Pleasantness *Measure

1, 112

0.180

0.672

Pleasantness *Group *Measure

1, 112

0.296

0.587

Medication *Source

1, 112

4.384

0.039*

Medication × Source *Group

1, 112

1.976

0.163

Medication × Source *Measure

1, 112

5.802

0.018*

Medication × Source *Group *Measure

1, 112

1.373

0.244

Medication × Pleasantness

1, 112

0.008

0.929

Medication × Pleasantness *Group

1, 112

0.007

0.935

Medication × Pleasantness *Measure

1, 112

0.051

0.822

Medication × Pleasantness *Group *Measure

1, 112

0.112

0.739

Source × Pleasantness

1, 112

1.103

0.296

Source × Pleasantness *Group

1, 112

0.081

0.777

Source × Pleasantness *Measure

1, 112

0.058

0.810

Source × Pleasantness *Group *Measure

1, 112

0.141

0.708

Medication × Source × Pleasantness

1, 112

0.033

0.855

Medication × Source × Pleasantness *Group

1, 112

0.966

0.328

Medication × Source × Pleasantness *Measure

1, 112

0.134

0.715

Medication × Source × Pleasantness *Group *Measure

1, 112

0.918

0.340

  1. *p < 0.05 **p < 0.01 ***p < 0.001.