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Figure 2 | Molecular Autism

Figure 2

From: Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis

Figure 2

Enriched pathways in Fmr1 -KO and Tsc2+/− models of ASD, found using the Gene Set Enrichment Analysis (GSEA). Red (upregulated) and blue (downregulated) squares in the matrix represent enriched pathways for each data set (false discovery rate ≤ 0.05). Two immune system pathways (cytokine-cytokine receptor signaling pathway and hematopoietic cell lineage) and one signaling pathway (cell communication) were significant in the brain gene expression profiles of both mice models.

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Molecular Autism

ISSN: 2040-2392