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Figure 3 | Molecular Autism

Figure 3

From: Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder

Figure 3

Independent replication of genome-wide significant linkage at 20p13. Genome-wide significant linkage signal at 20p13 from the combined sample (ALL fams; green, solid line), Autism Genetics Resource Exchange families (AGRE fams) analyzed by Weiss et al.[33] (orange, dashed line), and all AGRE families not previously analyzed by Weiss et al. [33] (Ind. Fams; purple, solid line). Top: linkage across the full chromosome 20; middle: linkage across a 2-logarithm of odds (LOD) interval from the peak LOD; bottom: RefSeq gene alignment in the 2-LOD interval. Dashed lines mark LOD thresholds corresponding to linkage P-values of 0.01, 0.001, and 0.0001 [35].

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Molecular Autism

ISSN: 2040-2392