Skip to main content

Table 1 Characteristics of the total genetic disorder sample

From: Behavioral signatures related to genetic disorders in autism

Genetic disorder N Age (months) ASD ADI-R scores per domain and total scores IQ
Total Female Male Yes No I II III Total
22q11DS 90 42 48 162.5 ± 33.6 40 50 9.8 ± 6.4 7.7 ± 4.8 2.5 ± 2.2 20.0 ± 12.0 67.0 ± 14.1
Down’s 21 16 5 169.1 ± 32.6 6 15 7.2 ± 4.4 6.8 ± 3.8 3.2 ± 2.0 17.2 ± 8.6 49.5 ± 11.9
PWS 88 48 40 191.9 ± 141.0 20 68 7.9 ± 5.1 5.7 ± 4.5 2.8 ± 2.0 16.3 ± 10.1 70.9 ± 16.3
SMC15 22 8 14 161.4 ± 103.6 19 3 15.6 ± 6.0 13.6 ± 5.5 6.5 ± 2.4 35.7 ± 12.2 51.0 ± 19.0
TSC 50 31 19 126.2 ± 74.0 22 28 12.0 ± 9.0 9.6 ± 6.8 3.7 ± 3.3 25.2 ± 17.9 69.3 ± 27.4
XXY 51 0 51 145.4 ± 41.4 16 35 8.5 ± 6.0 8.8 ± 5.4 2.3 ± 2.1 19.6 ± 12.0 80.4 ± 13.9
Total 322 145 177   123 199      
Average     162.7 ± 89.8    9.6 ± 6.7 8.0 ± 5.6 3.1 ± 2.5 20.6 ± 13.4 68.6 ± 19.2
  1. Data provided are mean values and, if applicable, standard error of the means. ADI-R domains: I, qualitative abnormalities in reciprocal social interaction; II, qualitative abnormalities in communication; and III, restricted, repetitive and stereotyped patterns of behavior. 22q11DS, 22q11.2 deletion syndrome; ADI-R, Autism Diagnostic Interview-Revised; ASD, autism spectrum disorder; Down’s, Down’s syndrome; PWS, Prader-Willi syndrome; SMC15, supernumerary marker chromosome 15; TSC, tuberous sclerosis complex; XXY, Klinefelter syndrome.